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Javier S Castresana Selected Research

lomeguatrib

2/2014Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.
6/2013Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.

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Javier S Castresana Research Topics

Disease

28Neoplasms (Cancer)
05/2021 - 01/2002
11Glioblastoma (Glioblastoma Multiforme)
05/2021 - 01/2002
8Neuroblastoma
11/2021 - 08/2007
7Medulloblastoma
09/2016 - 09/2004
6Astrocytoma (Pilocytic Astrocytoma)
04/2019 - 01/2002
6Glioma (Gliomas)
04/2015 - 02/2011
4Brain Neoplasms (Brain Tumor)
05/2021 - 09/2003
4Primitive Neuroectodermal Tumors (PNET)
06/2011 - 12/2004
3Meningioma (Meningiomas)
06/2015 - 01/2010
3Acoustic Neuroma (Acoustic Neurinoma)
09/2013 - 01/2013
3Neurilemmoma (Schwannoma)
05/2013 - 01/2010
1Spontaneous Remission
01/2014
1Oligodendroglioma
08/2013
1Carcinogenesis
07/2013
1Ewing Sarcoma (Sarcoma, Ewing)
06/2011
1Neoplasm Metastasis (Metastasis)
11/2010

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
11/2021 - 09/2002
6Temozolomide (Temodar)FDA LinkGeneric
01/2021 - 04/2009
5Biological ProductsIBA
09/2013 - 09/2003
4DNA (Deoxyribonucleic Acid)IBA
06/2015 - 03/2008
3EnzymesIBA
05/2019 - 01/2002
2Tumor Suppressor Protein p14ARF (p14ARF)IBA
11/2021 - 01/2012
2MicroRNAs (MicroRNA)IBA
03/2021 - 01/2013
2PanobinostatIBA
01/2021 - 01/2020
2FurinIBA
04/2019 - 01/2002
2Transforming Growth Factor beta (TGF-beta)IBA
10/2016 - 01/2002
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
03/2015 - 08/2013
2lomeguatribIBA
02/2014 - 06/2013
2Cyclin-Dependent Kinase Inhibitor p16IBA
01/2012 - 01/2003
2Cyclin D2IBA
02/2011 - 11/2010
2gamma Catenin (Plakoglobin)IBA
02/2011 - 11/2010
2ParaffinIBA
08/2007 - 12/2004
2Metalloproteases (Metalloproteinases)IBA
09/2003 - 01/2002
1Antineoplastic Agents (Antineoplastics)IBA
11/2021
1Histone Deacetylase 6IBA
05/2021
1Protein Isoforms (Isoforms)IBA
05/2021
1Cadherins (E-Cadherin)IBA
05/2021
1eprenetapoptIBA
01/2021
1alpha-SynucleinIBA
05/2020
1Histone Deacetylase InhibitorsIBA
01/2020
1Histones (Histone)IBA
05/2019
1Peptides (Polypeptides)IBA
10/2016
1SuspensionsIBA
09/2016
1Laminin (Merosin)IBA
09/2016
1X-linked Nuclear ProteinIBA
03/2015
1Pharmaceutical PreparationsIBA
12/2014
1Culture MediaIBA
01/2014
12-toluenesulfonamide (OTS)IBA
08/2013
1Neurofibromin 1 (Neurofibromin)IBA
07/2013
1Androgen Receptors (Androgen Receptor)IBA
03/2013
1OsteopontinIBA
03/2013
1IntegrinsIBA
03/2013
1Neuregulin-1 (Neuregulin 1)IBA
03/2013
1Neurofibromin 2 (Merlin)IBA
03/2013
1Caveolin 1IBA
03/2013
1Messenger RNA (mRNA)IBA
03/2013
1Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2013
1LigandsIBA
11/2011
1Imatinib Mesylate (Gleevec)FDA Link
06/2011
1Stem Cell FactorIBA
06/2011
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
06/2011
1CateninsIBA
02/2011
1WD repeat containing planar cell polarity effectorIBA
02/2011
1Zinc Finger Protein GLI1IBA
02/2011
1Patched-1 ReceptorIBA
02/2011
1Small Interfering RNA (siRNA)IBA
11/2010
1cyclopamineIBA
10/2010
1Complementary DNA (cDNA)IBA
01/2010
1RNA (Ribonucleic Acid)IBA
01/2010
1trichostatin A (A 300)IBA
03/2008
1DecitabineFDA Link
03/2008
1theasinensin AIBA
03/2008
1Caspase 8 (Caspase-8)IBA
09/2004
1Matrix Metalloproteinase 3 (Stromelysin 1)IBA
09/2003
1GelatinasesIBA
09/2003
1N- (2(R)- 2- (hydroxamidocarbonylmethyl)- 4- methylpentanoyl)- L- tryptophan methylamideIBA
09/2003
1TensinsIBA
01/2003
1ErbB Receptors (EGF Receptor)IBA
01/2003
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2003
1Cyclin-Dependent Kinase 4IBA
01/2003
1E2F1 Transcription FactorIBA
09/2002
1Insulin-Like PeptidesIBA
01/2002

Therapy/Procedure

9Therapeutics
11/2021 - 01/2002
6Drug Therapy (Chemotherapy)
11/2021 - 12/2012
2Radiotherapy
01/2021 - 01/2020
1Ligation
01/2014
1Aftercare (After-Treatment)
10/2010